Charley Darkey Parkhurst (born Charlotte Darkey Parkhurst; 1812 – December 18, 1879) also known as "One-Eyed Charley" or "Six-Horse Charley", was an American stagecoach driver, farmer and rancher in California. Raised female in New England, Parkhurst ran away as a youth, taking the name Charley and began living as a man. He started work as a stable hand and learned to handle horses, including to drive coaches drawn by multiple horses. He worked in Massachusetts and Rhode Island, traveling to Georgia for associated work.

In his late 30s, Parkhurst sailed to California following the Gold Rush in 1849; there he became a noted stagecoach driver. In 1868, he may have been the first person of the female sex to vote in a presidential election in California. After his death in 1879, his sex was discovered by others, as well as that he had given birth at an earlier time.